Characteristics of phagocytosis of Yersinia pseudotuberculosis with various sets of plasmids
Dubrovina, V.I.; Golubinskiĭ, E.P.; Borsuk, G.I.; Balakhonov, S.V.; Konovalova, Z.A.
Meditsinskaia Parazitologiia i Parazitarnye Bolezni 4: 50-53
1999
ISSN/ISBN: 0025-8326 PMID: 11221008 Document Number: 498800
The study used the selected aplasmid strain of Y. Pseudotuberculosis 53 and I-716, which contains plasmids that have molecular weights of 48 and 82 mD, and I-727 that has only virulence plasmid pYV48. The study has indicated that the fact that Yersinias have pVM82 and pYV48 enhances their resistance to phagocytosis. The Y. pseudotuberculosis strains carrying these plasmids suppress the responsiveness of phagocytes, inhibit an "oxidative explosion", lower the activities of superoxide dismutase and myeloperoxidase, thus suppressing their bactericidal capacity.