Antigenic activity of measles immunostimulating complex
Mamaeva, T.A.; Tikhonova, N.T.; Starov, A.I.; Naumova, M.A.; Vysotskiĭ, V.V.
Voprosy Virusologii 43(3): 127-129
1998
ISSN/ISBN: 0507-4088 PMID: 9702812 Document Number: 497813
The liposomal technology for preparing the immunostimulating complex (ISCOM) helped obtain a complex measles preparation whose antigens are represented by the structural proteins of measles virus in the bilayer phosphate-lipid membrane. Immunization of mice with the resultant preparation induced antimeasles antibodies with the maximum titer of antihemagglutinins 1:640 and of antihemolysins 1:1280. The biological activity of antibodies was confirmed in the neutralization test.
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