Adult T-cell leukemia-lymphoma due to HTLV 1. two cases of the acute form at the Principal Hospital of Dakar
Mbaye, P.S.; Talarmin, F.; Ndoye, B.; Gueye, P.M.; Camara, P.; Sane, M.; Klotz, F.
Dakar Medical 43(2): 228-230
1998
ISSN/ISBN: 0049-1101 PMID: 10797970 Document Number: 495990
HTLV1 virus is a retrovirus that has been endemic in Africa. It is the responsible for tropical spastic paraparesis and adult's T Cell leukemia-lymphoma. Few cases of adult T-Cell leukemia-lymphoma have been described in Africa, contrary to Japan and Caribbean. Were are reporting two cases of acute adult T-Cell leukemia-lymphoma which characterised by blood lymphoma signs, tumoral nodes and extranods lesions, hypercalcemia and positive retroviral serology of HTLV1 virus. The prognosis of these acute forms was bad after a six month survey approximately. The treatment is disappointing. Investigations of this affection must be carried out in every patient who presents lymphoma manifestations all the more because they are associated with hypercalcemia.