The 1st case of adult T-cell leukemia (ATL) with expressed immune response to HTLV in the USSR
Gurtsevich, V.E.; Seniuta, N.B.; Pivnik, A.V.; Pavlish, O.A.; Stepina, V.N.; Syrtsev, A.V.; Iakhnina, E.I.; Kremenetskaia, A.M.
Voprosy Onkologii 37(5): 563-568
1991
ISSN/ISBN: 0507-3758 PMID: 1767511 Document Number: 371454
The first of case of adult T-cell prolymphocytic lymphosarcoma is reported which according to the natural course, cell composition of tumor, cell surface markers as well as expressed immune response to a wide spectrum of HTLV-1 gag an env encoded proteins can be classified as HTLV-associated adult T-cell leukemia. Diagnosis of the tumor alongside with identification of HTLV-1-infected individuals in the USSR emphasizes the need to stimulate research in HTLV-1-associated carcinogenesis in this country.