Top Abstract Purchase Related
Home
>
Node
>
Subnode

Morphometric characteristics of Leydig cells after total irradiation of rats treated with melatonin

Mornjaković, Z.; Alicelebić, S.; Bilalović, N.; Susko, I.

Medicinski Arhiv 52(4): 183-184

1998

ISSN/ISBN: 0025-8083
PMID: 10321058
Document Number: 495703
The aim of the study was to determine the effects of exogenous melatonin on Leydig cells in irradiation stress. Nuclear and cytoplasm surface of Leydig cells in sham pinealectomized and pinealectomized adult Wistar rats was determined after their total irradiation with 8 Gy of gama rays produced by 60 Co and with previously performed 14 days treatment by injecting of melatonin solution in a daily dose of 0.2 mg. Rats testes were histologically prepared 17 days after irradiation. Total melatonin administration significantly decreased surface of Leydig cells including both decrease of their nuclear and cytoplasm surface in irradiated sham pinealectomized and pinealectomized rats. The results suggested about direct effects of exogenous melatonin on Leydig cells in irradiation stress.

Document emailed within 1 workday
Secure & encrypted payments

Goh, K.O. 1973: Total body irradiation and human chromosomes. 3. Cytogenetic studies in patients with malignant hematologic diseases treated with total-body irradiation American Journal of the Medical Sciences 266(3): 179-186
Adeyemi, D.O.; Komolafe, O.A.; Adewole, O.S.; Obuotor, E.M.; Abiodun, A.A.; Adenowo, T.K. 2010: Histomorphological and morphometric studies of the pancreatic islet cells of diabetic rats treated with extracts of Annona muricata Folia Morphologica 69(2): 92-100
Oluwole, S.; Hardy, M.A.; Fawwaz, R.; Todd, G.; Nowygrod, R.; Reemtsma, K. 1979: Selective lymphoid irradiation. II. Comparison with total-body irradiation on cardiac allograft survival in rats Transplantation 28(6): 492-495
Chukwuemeka, N.; Philippe, M.; Magdalene, N.; Onyezuligbo, O. 2012: Effects of total body irradiation on fatty acid and total lipid content of rats Pakistan Journal of Pharmaceutical Sciences 25(1): 169-173
Pospísilová, J.; Kamarád, V. 1987: Quantitative morphometric evaluation of changes in the small intestine mucosa of laboratory rats after X-ray and gamma irradiation Acta Universitatis Palackianae Olomucensis Facultatis Medicae 117: 31-39
Anavi, B.; Danev, V. 1990: Megatubules in renomedullary and Leydig interstitial cells in rats Folia Medica 32(1): 45-50
Tai, J.; Tze, W.J.; Yip, S.; Johnson, H.J. 1992: Transplantation studies of Leydig cells in castrated inbred rats Transplantation Proceedings 24(6): 2917-2919
Sun, J.; Shi, C.-R.; Xi, Y.-B.; Li, W.-Y.; Li, H.-Y. 2008: Allotransplantation of Leydig cells increases serum testosterone in rats Zhonghua Nan Ke Xue 14(9): 823-825
Olivares, A.N.; Valladares, L.E.; Bustos-Obregón, E.; Núñez, S.M. 1989: Testicular function of sexually immature rats chronically treated with melatonin Archivos de Biologia Y Medicina Experimentales 22(4): 387-393
Grochowski, D.; Szamatowicz, M. 1989: The role of gonadotropins, cyclic AMP, 22-R-hydroxycholesterol and cofactors in regulating endocrine functions of the Leydig cells in rats. II. Effects of LH, hCG, dbcAMP, 22-R-OH-cholesterol and cofactors on the synthesis of pregnenolone and testosterone in the interstitial gland of rats Ginekologia Polska 60(5): 246-251
Barinov, E.F.; Sulaeva, O.N. 2003: Morphometric characteristics of the kidney nephrogenic zone in newborn rats Morfologiia 123(2): 77-80
Shevliuk, N.N. 1995: The morphofunctional characteristics of the interstitial endocrinocytes (Leydig cells) of the testes in vertebrates under conditions of seasonal change in reproductive activity Morfologiia 108(2): 57-60
Zhong, L.; Ju, G.-Q.; Liu, G.-H.; Sun, J. 2018: Mechanisms of stem cell-derived extracellular vesicles protecting Leydig cells from acute oxidative injury in rats Zhonghua Nan Ke Xue 24(1): 14-18
Riotte, M.; Nouaille-Degorce, J.; Vacquier, M.; Chaumont, A.; Cier, A. 1971: Renewal of cerebral catecholamines after total irradiation in rats Journal de Physiologie 63(6): 276A-277A
Bachetoni, A.; Cinti, P.; Sallusto, F.; Poli, L.; Pretagostini, R.; Alfani, D.; Renna Molajoni, E.; Cortesini, R. 1991: Immunological studies of renal allograft recipients treated with total lymphoid irradiation Allergologia et Immunopathologia 19(2): 69-77
Vriesendorp, H.M.; Heidt, P.J.; Zurcher, C. 1981: Gastrointestinal decontamination of dogs treated with total body irradiation and bone marrow transplantation Experimental Hematology 9(9): 904-916
Chaĭchenko, H.M. 1975: The effect of total x-irradiation on the lability of nervous processes in young rats Fiziolohichnyi Zhurnal 21(3): 337-342
Danilova, O.A.; Khristich, M.; Chernigovskaia, E.V. 1982: Morphometric characteristics of the development of the neurosecretory cells in the hypothalamic center in the rat during postnatal ontogeny Arkhiv Anatomii Gistologii i Embriologii 82(3): 5-10
Hill, S.M.; Blask, D.E. 1988: Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture Cancer Research 48(21): 6121-6126
Vasil'eva, L.A.; Burykina, L.N.; Likhacev, I.P. 1979: Blastomogenic action of combined total x-ray irradiation and the administration of 131i on young rats Voprosy Onkologii 25(7): 53-55