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Effects of leukotrienes on production of interleukin 6 from mouse peritoneal macrophages

Zhong, M.; Cheng, G.; Wang, W.; Zhou, L.; Zhu, X.; Zhang, J.

Yao Xue Xue Bao 33(5): 326-329

1998

ISSN/ISBN: 0513-4870
PMID: 12016997
Document Number: 494774
In the present study, effects of leukotrienes on IL-6 production by mouse resident peritoneal macrophages were explored with a bioassay method involving IL-6 dependent murine hybridoma B9 cell line. The results showed that LTB4, LTC4 and LTD4 can enhance the production of IL-6 from cultured peritoneal macrophages of mice. The optimal concentractions for LTB4, LTC4 and LTD4 were found to be 1.45 x 10(-6), 6.9 x 10(-8) and 8.05 x 10(-8) mol.L-1, respectively. The results suggest that peptide leukotrienes might play important role on IL-6 production in the local milieu of inflammation.

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Qiu, H.B.; Chen, D.C.; Pan, J.Q.; Liu, D.W.; Ma, S. 1999: Inhibitory effects of nitric oxide and interleukin-10 on production of tumor necrosis factor alpha, interleukin-1 beta, and interleukin-6 in mouse alveolar macrophages Zhongguo Yao Li Xue Bao 20(3): 271-275
Hu, Z.L.; Zhang, J.P.; Qian, D.H.; Lin, W.; Xie, W.F.; Zhang, X.R.; Chen, W.Z. 1996: Effects of matrine on mouse splenocyte proliferation and release of interleukin-1 and -6 from peritoneal macrophages in vitro Zhongguo Yao Li Xue Bao 17(3): 259-261
Takeshita, K.; Yamagishi, I.; Harada, M.; Otomo, S.; Nakagawa, T.; Mizushima, Y. 1989: Immunological and anti-inflammatory effects of clarithromycin: inhibition of interleukin 1 production of murine peritoneal macrophages Drugs under Experimental and Clinical Research 15(11-12): 527-533
Li, J.; Jiang, Y.Y.; Yue, T.L. 1989: Inhibition of release of prostaglandins and leukotrienes from calcimycin-induced mouse peritoneal macrophages and bovine aorta endothelial cells by anisodamine Zhongguo Yao Li Xue Bao 10(3): 274-278
Bender, J.G.; Stewart, C.C.; Van Epps, D.E.; Walker, D.E. 1990: 13-cis retinoic acid augments the production of macrophages in mouse bone marrow cultures stimulated with interleukin 3 Experimental Hematology 18(9): 990-994
Ju, D.W.; Zheng, Q.Y.; Wang, H.B.; Guan, X.J.; Fang, J.; Yi, Y.H. 1994: Inhibitory effects of esculentoside A on mouse macrophages and antibody production Yao Xue Xue Bao 29(4): 252-255
Thyberg, J.; Hellgren, D.; Blomgren, K. 1981: Effects of colchicine on acid hydrolase secretion by cultured mouse peritoneal macrophages European Journal of Cell Biology 26(1): 168-176
Luo, X.; Yu, M.-Y.; Xu, X.-Y.; Zeng, J.; Jiang, N.; Zheng, L.-Y. 2008: Effects of Armillariella tabescens polysaccharide IPS-B2 on activity of mouse peritoneal macrophages and transcription of related gene Zhongguo Zhong Yao Za Zhi 33(11): 1305-1308
Shamsuddin, M.; Hsueh, W.; Smith, L.J. 1992: Production of leukotrienes and thromboxane by resident and activated rat alveolar macrophages: a possible role of protein kinase C Journal of Laboratory and Clinical Medicine 120(3): 434-443
Hu, Z.L.; Qian, D.H. 1993: Effects of protein kinase C activator and inhibitor on release of tumor necrosis factor from mouse peritoneal macrophages Zhongguo Yao Li Xue Bao 14(2): 183-186
Thyberg, J. 1980: Internalization of cationized ferritin into the Golgi complex of cultured mouse peritoneal macrophages. Effects of colchicine and cytochalasin B European Journal of Cell Biology 23(1): 95-103
Zhang, X.; Morrison, D.C. 1993: Pertussis toxin-sensitive factor differentially regulates lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production in mouse peritoneal macrophages Journal of Immunology 150(3): 1011-1018
Osato, J.A.; Korkina, L.G.; Santiago, L.A.; Afanas'ev, I.B. 1995: Effects of bio-normalizer (a food supplementation) on free radical production by human blood neutrophils, erythrocytes, and rat peritoneal macrophages Nutrition 11(5 Suppl): 568-572
De Bakker, J.M.; De Wit, A.W.; Onderwater, J.J.; Ginsel, L.A.; Daems, W.T. 1985: On the origin of peritoneal resident macrophages. I. DNA synthesis in mouse peritoneal resident macrophages Journal of Submicroscopic Cytology 17(2): 133-139
Lee, K. 1985: Superoxide anion (O2-) release from mouse peritoneal macrophages associated with ingestion of mycobacteria and effects of O2- on intracellular multiplication of mycobacteria Kekkaku: 60(1): 23-30
Liu, Y.; Luo, L.; Zhao, H. 2000: Changes of tumor necrosis factor alpha and interleukin-6 levels in peritoneal fluid of patients with endometriosis and their effects on human sperm motility and mouse embryo development Zhonghua Fu Chan Ke Za Zhi 35(6): 332-334
De Bakker, J.M.; De Wit, A.W.; Koerten, H.K.; Ginsel, L.A.; Daems, W.T. 1985: On the origin of peritoneal resident macrophages. III. EM-immunocytochemical studies on the origin of mouse peritoneal resident macrophages Journal of Submicroscopic Cytology 17(2): 153-159
Shimoda, K.; Okamura, S.; Harada, N.; Omori, F.; Niho, Y. 1990: Production of interleukin-6 from macrophages by MDP-Lys (L 18), romurtide Research Communications in Chemical Pathology and Pharmacology 70(3): 289-296
Yamamoto, N.; Homma, S.; Millman, I. 1991: Identification of the serum factor required for in vitro activation of macrophages. Role of vitamin D3-binding protein (group specific component, Gc) in lysophospholipid activation of mouse peritoneal macrophages Journal of Immunology 147(1): 273-280
Titov, V.N. 2003: The role of macrophages in inflammation development, effects of interleukin-1, interleukin-6, and hypothalamo-hypophyseal system activity (a literature review) Klinicheskaia Laboratornaia Diagnostika 2003(12): 3-10