Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effects of chronic systemic administration of opioid peptides, naloxone and N-acetyl beta-endorphin antiserum on gonadotropins and testicular functions in the rat

Laxmi, N.A.; Vijayan, E.

Indian Journal of Experimental Biology 36(4): 361-366

1998

ISSN/ISBN: 0019-5189
PMID: 9717445
Document Number: 490716
Systemic administration of opioid peptides, methionine-enkephalin and beta-endorphin, chronically, lowered gonadotropin levels in plasma and had an inhibitory effect mainly on the testicular enzymes hyaluronidase, acid phosphatase and on incorporation of 3(H) thymidine in the tissue. When rats were similarly treated with opioid peptide antagonist naloxone and N-acetyl beta-endorphin antiserum, induced an opposite effect. This is either the direct effect of opioid peptides/antagonist on the gonads or it may be via the circulating levels of gonadotropin.

Document emailed within 1 workday
Secure & encrypted payments

Burbach, J.P.; Loeber, J.G.; Verhoef, J.; Wiegant, V.M.; de Kloet, E.R.; de Wied, D. 1980: Selective conversion of beta-endorphin into peptides related to gamma- and alpha-endorphin Nature 283(5742): 96-97
Drennan, I.R.; Orkin, A.M. 2016: OPIOID CRISIS. Prehospital naloxone administration for opioid-related emergencies Jems: a Journal of Emergency Medical Services 41(3): 36-39
Kuhn, E.; Lodin, Z.; Lovacký, S.; Tauber, O.; Zizkovský, V.; Dvorák, P.; Srajer, S.; Skála, I. 1986: Plasma beta-endorphin immunoreactivity (PL-beta-ED-ir) in patients with ulcer disease and its management by acute and chronic administration of gastrozepin Hepato-Gastroenterology 33(1): 23-26
Schoffelmeer, A.N.; Yao, Y.H.; Gioannini, T.L.; Hiller, J.M.; Ofri, D.; Roques, B.P.; Simon, E.J. 1990: Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex Journal of Pharmacology and Experimental Therapeutics 253(1): 419-426
Lin, J.; Lu, G.; Weng, J. 1994: Effects of beta-endorphin on phytohemagglutinin-induced lymphocyte proliferation and mouse plaque-forming cell response via an opioid receptor mechanism Chinese Medical Sciences Journal 9(4): 245-247
Farsang, C.; Kapocsi, J.; Varga, K.; Vajda, L.; Balás-Eltes, A.; Kunos, G. 1985: Beta-Endorphin and essential hypertension: importance of the clonidine-naloxone interaction Acta Physiologica Hungarica 65(2): 217-226
Rees, M.; Bowen, J.C.; Payne, J.G.; MacPhee, A.A. 1983: Plasma beta-endorphin immunoreactivity in dogs during anesthesia, surgery, Escherichia coli sepsis, and naloxone therapy Surgery 93(3): 386-390
Pasi, A.; Meyer, M.; Boltshauser, E.; Foletta, D.; Gramsch, C. 1982: Failure of naloxone to reverse analgesia in congenital insensitivity to pain, and variable plasma levels of beta-endorphin-like activity Lancet 1(8272): 622
Hammonds, R.G.; Westphal, M.; Li, C.H. 1985: Beta-endorphin: photoaffinity labelling of a non-opioid binding site in a human neuroblastoma Biochemical and Biophysical Research Communications 128(3): 1310-1314
Matsukura, S.; Yoshimi, H. 1978: Beta-lipotropin and opioid peptides Nihon Rinsho. Japanese Journal of Clinical Medicine 36(1): 159-165
Celio, M.R.; Höllt, V.; Buetti, G.; Pasi, A.; Bürgisser, E.; Eberle, A.; Kopp, G.; Siebenmann, R.; Friede, R.L.; Landolt, A.; Binz, H.; Zenker, W. 1980: Immunohistochemical study of beta-endorphin and related peptides in the "invading cells" of the human neurohypophysis during ontogenesis and adulthood Advances in Biochemical Psychopharmacology 22: 271-283
Dixit, V.P.; Joshi, S. 1982: Effects of chronic administration of garlic (Allium sativum Linn) on testicular function Indian Journal of Experimental Biology 20(7): 534-536
Bhanalaph, T.; Mittelman, A.; Ambrus, J.L.; Murphy, G.P. 1973: Effects of chronic administration of adenosine on kidney and liver functions Journal of Medicine 4(3): 189-192
Smith, E.M.; Dion, L.D.; Blalock, J.E. 1985: Opiate receptor mediated effects of IFN-alpha and lymphocyte derived endorphin-like peptides Progress in Clinical and Biological Research 192: 259-264
Makise, J.; Saito, E.; Obuchi, M.; Kanayama, M.; Harakawa, K.; Yoshida, K. 1990: Improved kinetic rate assay of urinary N-acetyl-beta-D-glucosaminidase with 2-chloro-4-nitrophenyl-N-acetyl-beta-D-glucosaminide as substrate Clinical Chemistry 36(2): 319-322
Clark, W.G. 1981: Effects of opioid peptides on thermoregulation Federation Proceedings 40(13): 2754-2759
Le Lannou, D.; Chambon, Y. 1977: Effects of ligation of the ductuli efferentes or the epididymis on testicular function and secretion of gonadotropins in rats Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 171(1): 197-200
Cerci, C.; Yildirim, M.; Ceyhan, M.; Bozkurt, S.; Doguc, D.; Gokicimen, A. 2008: The effects of topical and systemic Beta glucan administration on wound healing impaired by corticosteroids Wounds: a Compendium of Clinical Research and Practice 20(12): 341-346
Bloch, B.; Lenys, D.; Gouget, A.; Fellmann, D.; Bugnon, C. 1979: Immunocytologic analysis, in rat hypothalamus, of neurons producing peptides related to endorphin, ACTH, MSH and beta-LPH. Comparison with other peptidergic and monoaminergic neurons Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 173(4): 719-724
Falk, J.L.; Ma, F.; Lau, C.E. 1991: Chronic oral cocaine self-administration: pharmacokinetics and effects on spontaneous and discriminative motor functions Journal of Pharmacology and Experimental Therapeutics 257(1): 457-465