Hormonal regulation of the Ca+ transport in blood and vascular cells
Tkachuk, V.A.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 84(10): 1006-1018
1998
ISSN/ISBN: 0869-8139 PMID: 10097268 Document Number: 490604
The main pathways of regulation of cytoplasm Ca2+ level with hormones and growth factors, as well as mechanisms of regulation of G-proteins, phospholipase C, Ca-channels, adenylate cyclase, guanylate cyclase, and protein kinase C, are discussed. Regulation of cytoplasm Ca2+ in vascular and blood cells with inositol phosphates, cAMP and cGMP, is stressed. The review summarises data on membrane receptors, G-proteins, protein kinases and their targets involved in regulation of Ca2+ turnover in platelets, endothelial and smooth muscle cells.