Homing viruses
Sikorski, R.; Peters, R.
Science 280(5371): 1956-1957
1998
ISSN/ISBN: 0036-8075 PMID: 9669951 Document Number: 489664
A promising method for high-frequency introduction of mutations into human cells has been discovered. David W. Russell at the University of Washington and colleague Roli Hirata have succeeded in uncovering a peculiar ability of adeno-associated virus to increase human gene targeting by orders of magnitude. Russell and Hirata's research is examined.
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