Novel drug delivery systems
Raynaud, F.
Idrugs the Investigational Drugs Journal 1(4): 399-401
1998
ISSN/ISBN: 1369-7056 PMID: 18465569 Document Number: 489150
In the last few years, research in the field of anticancer drug development has adopted a number of novel approaches. Some of these new therapies have already reached the clinic. These include drugs stimulating cytokine production, drugs affecting the cell cycle, monoclonal antibodies, anti-angiogenic compounds, gene therapy, antisense therapy and vaccines. These new targets and strategies for cancer treatment require new guidelines for preclinical research and for performing phase I and phase II trials. The identification of surrogate endpoints for efficacy in preclinical and clinical trials is a new challenge for both scientists and clinicians.