Human papillomaviruses are not associated with renal carcinoma
Grce, M.; Furcić, I.; Hrasćan, R.; Husnjak, K.; Krhen, I.; Mareković, Z.; Zeljko, Z.; Pavelić, K.
Anticancer Research 17(3c): 2193-2196
1997
ISSN/ISBN: 0250-7005 PMID: 9216686 Document Number: 476280
In an attempt to better understand the troubling issue of renal human papillomavirus (HPV) infection, fresh tumour specimens obtained by surgical extirpation from tumours were compared for the presence of HPV. All of the renal carcinoma samples were examined by PCR using two sets of consensus primers and the specific primer pairs for HPV 16, 18, and 33. None of the 28 carcinomas and 17 corresponding normal tissues were found positive for HPV DNA in any of the applied analyses. Our results suggest that HPV does not play any role in the development of renal carcinoma in the general population.