The detection of human papillomaviruses in histological preparations by using dot-blot hybridization
Anton, G.; Stoian, M.; Iliescu, R.; Popa, L.M.; Repanovici, R.
Revue Roumaine de Virologie 43(3-4): 141-148
1992
ISSN/ISBN: 1018-0532 PMID: 1339203 Document Number: 399761
The 56 tissue samples were obtained from female patients with anogenital tumors, benign or malign, subsequently confirmed through pathomorphological analysis. The investigations were aimed at the discovering of HPV presence using hybridization techniques with biotinylated molecular probes and monitorisation through enzymatic reaction. The presence of ADN types 11, 16 and 18 was detected on about 52% of all the cases; the ADN HPV incidence was 57% among the patients with a neoplasm and/or cervix uteri papillomatosis diagnosis.