Laryngeal sarcomatoid carcinoma: clinical, histological and immunohistochemical study of four cases
Castaño Zapatero, I.; Pastor Quirante, F.A.; Redondo Luciáñez, E.R.
Acta Otorrinolaringologica Espanola 48(8): 630-634
1997
ISSN/ISBN: 0001-6519 PMID: 9580284 Document Number: 475982
The purpose of this study was to confirm how the use of immunohistochemical techniques can help to differentiate between tumors with a mixed proliferative pattern (epithelial and mesenchymal). It is fundamental to differentiating tumors of these characteristics in order to determine the prognosis and plan treatment. We used different techniques on tissue samples from four cases diagnosed as laryngeal sarcomatoid carcinoma. The results demonstrated that all four were sarcomatoid carcinomas, which correlated with the patients' favorable clinical evolution. The immunohistochemical study was useful for differentiating tumor type in the case of a biopsy specimen obtained from a mixed-pattern neoplasm.