Diagnostic criteria and prognosis of mediastinal lesions in children with lymphosarcoma
Gordina, G.A.; Makhonova, L.A.; Kiselev, A.V.; Peterson, I.S.; Koshechkina, N.A.; Tupitsin, N.N.
Voprosy Onkologii 43(4): 407-409
1997
ISSN/ISBN: 0507-3758 PMID: 9381690 Document Number: 474702
Treatment for mediastinal lymphosarcoma was given to 71 patients, aged 3-14 years, at the Institute's Clinics during 1982-1991. In that group, there were more males than females (3.4:1), mean duration of the condition of 3 months, T-cell immunity pattern (89.9%), enlarged anterior mediastinal lymph nodes and thymus, pleural lesions including pleuritis, mean mediastinal-thoracic index of 0.5, compression syndrome, elevated concentration of lactate dehydrogenase and presence of tumor cells in the bone marrow and peripheral blood. Among major negative factors of prognosis were inadequate therapy, pleural lesions and stage IV tumor.