Immunoenzyme assay for detection of natural antibodies against catecholamines
Miagkova, M.A.; Trubacheva, Z.N.; Panchenko, O.I.
Klinicheskaia Laboratornaia Diagnostika 3: 8-10
1997
ISSN/ISBN: 0869-2084 PMID: 9410467 Document Number: 474034
Solid-phase enzyme immunoassay (EIA) for detecting natural antibodies to catecholamines (dopamine, adrenaline, and noradrenaline) has been developed. For this purpose catecholamine antigens were synthesized on polymeric matrix. Optimal conditions for EIA detecting antibodies to these antigens in the sera of donors and patients with schizophrenia and disseminated sclerosis were defined. The levels of antibodies to dopamine, adrenaline, and noradrenaline are constant in donors and shifted in the patients.
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