The immunoenzyme test system for detection of HIV-1 antigens based on using immune polyclonal anti-HIV serum and monoclonal antibodies against gene GAG HIV-1 proteins
Trushinskaia, G.N.; Simonov, V.I.; Makarova, N.E.; Nosik, D.N.; Kushch, A.A.; Gibadulin, R.A.
Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 1992(9-10): 43-47
1992
ISSN/ISBN: 0869-6047 PMID: 1283720 Document Number: 401901
The paper describes the enzyme immunoassay system for detection of human immunodeficiency virus antigens, which is based on the use of rabbit anti-HIV antibodies and monoclonal antibodies to HIV-1 gene proteins gag. The system may be useful in the examination of laboratory and clinical samples to reveal both free and conjugated antigens in the composition of immune complexes. The sensitivity of the assay system under development is 0.5 ng/ml at 100% specificity.