Simplification of immune adherence hemagglutination test for detection of rabies antibodies in human serum
Zanetti, C.R.; Tino, M.S.; Chamelet, E.L.; Ishizuka, M.M.; Pereira, O.A.
Revista do Instituto de Medicina Tropical de Sao Paulo 31(5): 341-345
1989
ISSN/ISBN: 0036-4665 PMID: 2629063 Document Number: 347407
In the present work the immune adherence hemagglutination test (IAHA) was standardized in a simplified procedure. This test showed good reproducibility, better than the classical mice serum neutralization test (SN). The tests showed high correlation degree: high titers in one test corresponded to high titers in the other one, and the same occurred with low titers. The IAHA test is extremely simple, fast to perform, and of low cost when compared to tests such as SN or indirect immunofluorescense (IIF). It also proved to be useful in less sophisticated laboratories or even as a screening test for the titration of rabies antibodies.