Ochratoxin induced hemolysis in rabbits
Zofair, S.M.; Mathew, S.; Verma, R.J.
Indian Journal of Experimental Biology 34(6): 592-593
1996
ISSN/ISBN: 0019-5189 PMID: 8792649 Document Number: 469041
A saline suspension of RBC when incubated with an increasing concentration (1 to 10 VBR-mu-g/ml) VBR of crude ochratoxin at 37 degree C for 16 hr showed a marked alteration in morphological characters followed by hemolysis. The effect was more pronounced with higher concentration of toxin. The result suggests extreme cytotoxic effect of ochratoxin on RBC leading to its lysis.
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