A novel adipocyte long chain fatty acid transport protein
Schaffer, J.E.
European Journal of Medical Research 1(4): 176-180
1996
ISSN/ISBN: 0949-2321 PMID: 9386266 Document Number: 460249
Uptake of long chain fatty acids (LCFAs) is a critical function of eukaryotic cells. In the past, a diffusional mechanism has been proposed for passage of these hydrophobic molecules across the plasma membrane. I have recently used an expression cloning strategy to identify a novel integral plasma membrane fatty acid transport protein (FATP), which functions as an LCFA transporter. FATP may play a pivotal role in alterations of cellular metabolism which occur in several pathophysiologic states.