Kinetics of trans- and cis-resveratrol (3,4&apos;,5-trihydroxystilbene) after red wine oral administration in rats

Bertelli, A.A.; Giovannini, L.; Stradi, R.; Urien, S.; Tillement, J.P.; Bertelli, A.; Bertelli, A.A; Giovannini, L; Stradi, R; Urien, S; Tillement, J.P; Bertelli, A

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Kinetics of trans- and cis-resveratrol (3,4',5-trihydroxystilbene) after red wine oral administration in rats

Bertelli, A.A.; Giovannini, L.; Stradi, R.; Urien, S.; Tillement, J.P.; Bertelli, A.

International Journal of Clinical Pharmacology Research 16(4-5): 77-81

1996

ISSN/ISBN: 0251-1649

PMID: 9172004

Document Number: 459122

Kinetics of trans- and cis-resveratrol (3,4',5-trihydroxystilbene), a natural compound from grape products, have been evaluated in rats after oral administration of red wine. Resveratrol concentrations were measured in plasma, heart, liver and kidneys. Tissue concentrations showed a significant cardiac bioavailability and strong affinity for liver and kidneys.