Role of urokinase in the management of experimental intraventricular hemorrhage in canine model - Part 1 : canine intraventricular blood cast model

Chand, A.K.; Rout, D.

Neurology India 41(2): 65-67

1995


ISSN/ISBN: 0028-3886
PMID: 29542489
Document Number: 454570
A Canine model of intraventricular blood cast was developed in nine adult dogs to study the feasibility and the benefit of Urokinase administration by intraventricular route. A simple ventricular cannulation techniques was described to inject 8cc of preformed autologous clot to develop an intraventricular "blood cast model". An indwelling ventricular catheter-reservoir system was placed for direct administration of Urokinase to induce rapid clot lysis.

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