Solitary eosinophilic granuloma of bone
Berchenko, T.N.
Arkhiv Patologii 57(1): 27-34
1995
ISSN/ISBN: 0004-1955 PMID: 7771926 Document Number: 450979
Clinico-anatomical and pathomorphological analysis is carried out in 80 cases of SEBG that were treated or consulted in the Institute during 1963-1993. The following stages of SEBG are distinguished: 1--accumulation and proliferation of histiocytes; 2--granulomatosis; 3--regression. Obviously all SEBG which regress spontaneously or by means of punctures with intrafocal administration of medical drugs pass through these stages. Distinguishing these stages is of practical significance as well for the differential diagnosis and prognosis. When granulomatous process is persistent, Langerhans cells having little proliferative potencies and apparently releasing biologically active substances, are able to stimulate the formation of their precursors in the marrow and thus of supporting the pathological focus.