Eosinophilic granuloma. the management of solitary lesions of bone
Greis, P.E.; Hankin, F.M.
Clinical Orthopaedics and Related Research 257: 204-211
1990
ISSN/ISBN: 0009-921X PMID: 2199118 Document Number: 350545
Solitary eosinophilic granuloma (EG) lesions of bone can represent diagnostic and treatment dilemmas for the orthopedic surgeon. A retrospective review of one institution's experience with isolated EG skeletal lesions over a 30-year period was undertaken. Solitary lesions responded well to most treatment modalities (e.g., curettage, excision, and irradiation) and infrequently resulted in functional impairment. While EG involvement in bone can be a manifestation of a systemic histiocytosis, single-focus skeletal involvement appears to be a benign pathophysiologic process.