Radiotherapy of solitary and multiple eosinophilic granulomas of bone (stage I)
Wiegel, T.; Sommer, K.; Knop, J.; Reuter, M.; Baumann, M.; Krüll, A.; Hübener, K.H.
Strahlentherapie und Onkologie Organ der Deutschen Rontgengesellschaft . 167(7): 403-406
1991
ISSN/ISBN: 0179-7158 PMID: 1858016 Document Number: 380307
Between 1957 and 1990 15 patients with solitary (stage Ia by Greenberger) and 2 patients with multiple (stage Ib) eosinophilic granuloma of the bone were treated by radiotherapy in 18 locations after previous surgery. The doses applied varied from 6 Gy to 42 Gy (median for patients under 18 years: 8 Gy, for patients over 18 years: 30 Gy). Median follow-up was 9 years (range, 0.3-33 years). Local control rate and survival were 100%. Three patients with granuloma developed a second granuloma within 13 years after primary diagnosis (two bone manifestations, one cutaneous manifestation). Long-term follow-up of patients with solitary eosinophilic granuloma is necessary.