Marek's disease and new approaches to its control
Zelník, V.
Acta Virologica 39(1): 53-63
1995
ISSN/ISBN: 0001-723X PMID: 7572471 Document Number: 446453
Marek's disease (MD) is a lymphoproliferative disorder induced by a herpesvirus. Several factors, including those virus-encoded and host-dependent, affect the course of the disease. Existing vaccination program is based on the use of attenuated strains of MD virus (MDV) serotype 1 and on strains of nononcogenic serotype 2 (MDV2) and serotype 3 (herpesvirus of turkeys - HVT) viruses. Failures resulting in disease progress have been reported and indicate need for production of new, more effective vaccines. It is likely that future development of MD vaccines will rely on recombinant molecules technology.