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The effect of noradrenaline and dopamine agonists and antagonists on oxygen consumption in some insect and crustacean species

Weischer, M.L.; Hano, R.

Arzneimittel-Forschung 45(9): 1032-1035

1995

ISSN/ISBN: 0004-4172
PMID: 7488307
Document Number: 445301
The effect of drugs on oxygen consumption in some invertebrate species (insect larvae and crustacea) was investigated. Insect larvae showed an increase in oxygen consumption under the influence of sympathomimetic drugs such as isoprenaline or orciprenaline which could be prevented by beta-receptor antagonists like propranolol or butoxamine. The drugs had no effect in crustacea. On the other hand, in these animals dopamine agonists of different chemical structure (amphetamine, apomorphine, lisuride) caused an increase in oxygen consumption whereas the dopamine antagonist metoclopramide had an opposite effect.

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