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Verapamil binding with the blood erythrocytes and cardiac output in myocardial infarct patients

Makolkin, V.I.; Gneushev, E.T.; Vakhliaev, V.D.; Gneusheva, I.A.; Shchedrina, I.S.

Eksperimental'naia i Klinicheskaia Farmakologiia 58(6): 26-28

1995

ISSN/ISBN: 0869-2092
PMID: 8704606
Document Number: 445062
In 14 patients with myocardial infarction the degree of verapamil binding with blood erythrocytes after a single oral administration (80 mg/kg) and the dependence pharmacological effect, the minute heart output (+ % MOC), on verapamil content in plasma and erythrocytes were studied. Intraindividual variability of verapamil distribution coefficients between erythrocytes and plasma (RBC/Ptot) is 9.7 +/- 2,3%, and it differs reliably from values of inter-individual variability of this index (33.7 +/- 3.3%).

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Volgin, E.G. 1972: Connection between the changes of cardiac output and peripheral resistance in the course of myocardial infarct Kardiologiia 12(7): 109-111
Lazarev, I.A.; Vasechkin, S.S.; Petrukin, A.V.; Kosminskiĭ, P.G.; Gromov, S.G. 1995: Correction of low cardiac output syndrome in the acute period of myocardial infarct by vasoselective calcium antagonists Anesteziologiia i Reanimatologiia 1995(3): 66-68
Izotova, N.P.; Grudtsyn, G.V.; Gratsianskiĭ, N.A. 1973: Content of free fatty acids in the blood of patients with acute myocardial infarct and disorders of the cardiac rhythm Kardiologiia 13(11): 79-83
Kazakov, I.M. 1981: Indicators of apparent blood viscosity and zeta-potential of the erythrocytes in acute myocardial infarct Vrachebnoe Delo 10: 8-10
De Lio, U.; Maiolino, P.; Trevisan, G.; Cappelletti, F.; Vincenzi, M. 1981: Incidence of arrhythmias in acute myocardial infarct treated with verapamil, digitalis and a verapamil-digitalis combination Bollettino Della Societa Italiana di Cardiologia 26(9): 857-865
Thiele, R.; Schuffenhauer, M.; Dawczinski, H.; Winnefeld, K. 1990: Magnesium level in serum and erythrocytes in patients with chronic coronary heart disease without myocardial infarct Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 45(22): 685-686
Aquaro, G.; Ravera, A.; Belli, R.; Rey, L.; Possavino, G.; Pavia, M.; Idone, P. 1981: Verapamil in the acute phase of myocardial infarct Bollettino Della Societa Italiana di Cardiologia 26(12): 2139-2141
Redmann, K.; Bollmann, G.; Mann, D.; Günther, C.; Fangohr, C. 1990: Cell electrophoretic and absorption spectrographic investigations of the indirect effect of ultraviolet light on erythrocytes of patients with myocardial infarct and other illnesses Folia Haematologica 117(1): 193-200
1994: ACE inhibitors in cardiac insufficiency and myocardial infarct. What happens after myocardial infarct? Zeitschrift für Kardiologie 83(11 Suppl): 1-4
Gol'dberg, G.A.; Chavdar, F.N.; Suriadnova, B.A.; Tatarchenko, I.P.; Rabinovich, B.I. 1980: Therapeutic use of nitroglycerin in pulmonary edema and cardiac asthma in myocardial infarct patients Kardiologiia 20(4): 21-25
Tunian, I.S.; Akopov, S.E.; Melikian, N.G.; Melkumova, A.G. 1983: Functional changes in thrombocytes and erythrocytes in myocardial infarct Kardiologiia 23(1): 99-100
Urbaszek, W.; Schauer, J.; Günther, K.; Pankau, H. 1976: The value of the diastolic pulmonary arterial pressure for the estimation of the cardiac functional capacity in patients with myocardial infarct Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 31(2): 314-317
Alps, B.J.; Calder, C.; Wilson, A. 1983: The beneficial effect of nicardipine compared with nifedipine and verapamil in limiting myocardial infarct size in baboons Arzneimittel-Forschung 33(6): 868-876
Titov, V.N.; Sanfirova, V.M.; Efremov, E.E.; Ovtrakht, N.V.; Rudnev, V.I. 1985: Dynamics of blood fibronectin in patients with myocardial infarct Laboratornoe Delo 4: 197-202
Krister, E.E.; Tydel'skaia, I.L.; Goldina, V.V.; Myslavskaia, I.S. 1971: Anticardiac antibodies in the blood of patients with myocardial infarct Vrachebnoe Delo 7: 14-17
Keefe, D.L.; Kates, R.E. 1982: Myocardial disposition and cardiac pharmacodynamics of verapamil in the dog Journal of Pharmacology and Experimental Therapeutics 220(1): 91-96
Shargorodskii, B.M.; Kats, I.A. 1973: The possible relationship between the antifibrillatory effect of inderal in experimental myocardial infarct and its effect on cardiac oxidation reduction processes and blood supply Kardiologiia 13(3): 81-87
Gogin, E.E.; Nesterenko, I.B. 1985: Information value of research on blood myoglobin in myocardial infarct patients Klinicheskaia Meditsina 63(1): 33-37
Efremushkin, G.G. 1980: Immunoglobulin content in the blood serum of myocardial infarct patients Kardiologiia 20(1): 37-42
Chernysheva, G.V. 1970: Blood coagulation activity in patients with circulatory insufficiency and myocardial infarct Terapevticheskii Arkhiv 42(2): 72-75