The effect of delta sleep-inducing peptide on catalytic properties of brain mitochondrial malate dehydrogenase
Khvatova, E.M.; Gaĭnullin, M.R.; Mikhaleva, I.I.
Biulleten' Eksperimental'noi Biologii i Meditsiny 119(2): 141-143
1995
ISSN/ISBN: 0365-9615 PMID: 7670034 Document Number: 444284
Delta sleep-inducing peptides proved to change malate dehydrogenase properties in the rat brain mitochondria. Regulatory effect of the peptide appeared in the stabilization of the enzyme catalytic properties at a higher level, which prevents their changes in hypoxic stress. Control of malate dehydrogenase due to a direct peptide effect on the mitochondrial membranes is suggested.
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