Serum brain natriuretic peptide and its role in acute coronary syndrome with different types of mitochondrial dysfunction
Vasiuk, I.A.; Kulikov, K.G.; Krikunova, O.V.; Krikunov, P.V.; Shabel'nikova, E.I.
Klinicheskaia Meditsina 91(3): 25-27
2013
ISSN/ISBN: 0023-2149 PMID: 23789447 Document Number: 665310
The level of serum brain natriuretic peptide (BNP) was measured in 236 patients with acute coronary syndrome. Some of them presented with mitochondrial dysfunction. None showed diagnostically significant BNP levels within 12 hours after admittance, but patients with unstable angina and BNP level below 80 pg/ml had the lowest risk of serious cardiovascular diseases. Marked mitochondrial dysfunction was associated with maximum BNP levels 12 hr and 14 days after hospitalization and mild dysfunction with minimal BNP concentration.