The ability of hemoglobin and myoglobin to evoke a spasm of the smooth musculature and to accelerate thrombocyte destruction. a description of serotonin-ferroprotein receptors
Simonenkov, A.P.; Fedorov, V.D.; Fedorov, A.V.; Stupin, V.A.; Zhirnikova, M.L.; Iunin, E.K.; Kondakov, S.A.
Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 12: 45-51
1995
ISSN/ISBN: 0869-6047 PMID: 8664603 Document Number: 440890
The previously unknown properties of ferroproteins (hemoglobin and myoglobin) to cause smooth muscle spasm and to accelerate platelet degradation are described in the paper. Ferroproteins are shown to interact with some serotonin receptors. Some serotonin receptors of smooth muscles and platelets which hemoglobin and myoglobin interact with are termed serotonin-ferroprotein receptors (S-Fe-pr-receptors). The found properties of ferroproteins provide a deep insight into the understanding of physiological and pathophysiological processes with the participation of hemoglobin, myoglobin, platelets, smooth muscles, serotonin, and serotonin receptors.