Serotonin as a photoprotector of the oxygen-transporting function of hemoglobin
Artiukhov, V.G.; Vashanov, G.A.
Biofizika 38(4): 580-583
1993
ISSN/ISBN: 0006-3029 PMID: 8364059 Document Number: 421020
Oxygen-binding properties of human hemoglobin modified by UV-light (240-400 nm) in dose range (1.51 + 6.04) x 10(2) J/m2 together with serotonin (10(-4) M) has been studied by means of spectrophotometry. UV-radiation results in increase of the oxygen affinity of hemoglobin. Serotonin displays the photoprotective effect on the hemoglobin oxygen-transport function. Mechanisms of photoprotection of the biogenic amine are proposed for discussion.