Variations in serum protein fractions following a continuous long term intake of eugynon and lyndiol by Iranian women
Kamyab, S.; Baghdiantz, A.; Motamedi, H.
Journal of Steroid Biochemistry 9(8): 811-812
1978
ISSN/ISBN: 0022-4731 PMID: 713559 DOI: 10.1016/0022-4731(78)90205-4Document Number: 438035
Serum total protein and protein fractions were estimated in 150 Iranian subjects, aged 18-41, who had used lyndiol (.15 mg mestranol plus 2.5 mg lynestrenol) and eugynon (.05 mg ethinyl estradiol plus .5 mg norgestrel) for 1-72 months. The control group consisted of 32 Iranian women who were age- and socioeconomic status-matched but had never used oral contraceptives before. A decrease was observed in albumin fraction and increases in alpha 1-alpha 2, and beta globulins were statistically significant (P .01 or P .02). Serum albumin decreased in 100% of patients, whereas the alpha and beta globulins increased in over 95% of the subjects. No statistically significant variation in gamma globulin was observed after intake of either eugynon or lyndiol. No dose response correlation was evident.