Bone mineral content of women with uterine fibromyomas
Rozenberg, S.; Ham, H.; Peretz, A.; Robyn, C.; Degueldre, M.
International Journal of Fertility and Menopausal Studies 39(2): 77-80
1994
ISSN/ISBN: 1069-3130 PMID: 8012443 Document Number: 431195
To determine if the bone mineral content (BMC) of women suffering from fibroids is different from that of the reference population. Cross-sectional retrospective study. Fifty-nine women suffering from fibroids, compared to the reference population. BMC was measured at the vertebral L2-L4 site (BMC-1) and at the midradius site (BMC-r). The patients with fibroids exhibited no significant difference in BMC-r). The patients with fibroids exhibited no significant difference in BMC-r, but had a significantly higher (P < or = .001) BMC-1 than the reference population. Since BMC-1 is mainly constituted by trabecular bone and BMC-r by cortical bone, and since trabecular bone is more sensitive to estrogens than cortical bone, it is suggested that a hyper-estrogenic state co-existing with fibroids may induce a slight protective factor against osteoporosis of the vertebral skeleton.