Preparation of appropriate diagnostic systems of monoclonal antibodies based on human thyroid hormone, and their use in clinical practice
Koriazova, L.K.; Kovalevskaia, G.I.; Sigal, E.R.; Pozdniakova, T.A.; Petrova, E.N.; Samoĭlova, V.E.; Vasilov, R.G.
Biulleten' Eksperimental'noi Biologii i Meditsiny 118(10): 433-435
1994
ISSN/ISBN: 0365-9615 PMID: 7532463 Document Number: 429687
Original methods for mouse immunization with human TSH preparations are presented as are the results of the tests of the primary clones of producer hybridomas. Twelve monoclonal antibodies specific to six antigenic regions were obtained. Enzyme immunoassay test system was developed which made it possible to diagnose hypo- and hyperthyroidism in clinical practice.
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