Screening for deletion in patients with Duchenne's myodystrophy by multiplex amplification
Chukhrova, A.L.; Malygina, N.A.; Poliakov, A.V.; Zaĭtseva, S.P.; Sitnikov, V.F.; Dadali, E.L.; Kamennykh, L.N.; Khrennikov, V.I.; Badalian, L.O.; Evgrafov, O.V.
Tsitologiia i Genetika 28(4): 80-83
1994
ISSN/ISBN: 0564-3783 PMID: 7801388 Document Number: 427915
Patients with Duchenne muscular dystrophy were analyzed using the method of polymerase chain reaction in order to reveal deletions in the dystrophin gene. Deletions of different lengths and locations were detected in 28 of 78 ill boys. The highest number of deletions was detected in the 3'-end of the gene (the 45-50th exons).