Report of the Scientific Working Group on the biochemistry and chemotherapy of schistososomiasis. Geneva, 30 January - 1 February 1984
Anonymous
TDR/SCH SWG5/841: 19
1984
Document Number: 427537
Topics discussed during the meeting included: pharmacokinetics, metabolism and mode of action of praziquantel, metrifonate, oxamniquine, oltipraz, amoscanate and niridazole; mode of action and structure-activity relationships of the nitroheterocycles; glucose and energy metabolism and the pathways of pyrimidine and purine metabolism; inter-tegumental transport mechanisms and acetyl choline, dopamine and serotonin; pharmacokinetic studies of niridazole and its metabolites in Filipinos and of oltipraz and oxamniquine in Sudanese; resistance to antischistosomal drugs (oxamniquine, hycanthone) in patients in Brazil.
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