An experimental study of the effect of Acanthopanax giraldii Harms on the central nervous system
Deng, H.Z.; Hou, L.B.; Sun, S.Y.; Li, S.Y.
Zhongguo Zhong Yao Za Zhi 19(3): 171-4 192
1994
ISSN/ISBN: 1001-5302 PMID: 7945845 Document Number: 426034
Experimental data indicated that Acanthopanax giraldii given intraperitoneally in mice had pronounced inhibitory effects on the CNS. It reduced the spontaneous activity, prolonged the hypnotic time of pentobarbital sodium and antagonised the amphetamine-induced hyperactivity. The results suggest that the sedative effect of A. giraldii is probably different from that of diazepam, but perhaps similar to that of reserpine.