Effect of simultaneous low level exposure of Pb and Cd on delta-ALAD and acetylcholinesterase activity in rats
Gupta, S.; Bhosale, S.; Pandya, K.
Indian Journal of Experimental Biology 32(11): 819-821
1994
ISSN/ISBN: 0019-5189 PMID: 7896311 Document Number: 425640
Dose dependent study was performed to identify subcritical level of Pb and Cd. Blood delta-ALAD activity was inhibited by (0.1 mg/kg body wt) of both lead and cadmium in isolation and combination, the extent of which increases with duration of exposure. Hepatic delta-ALAD activity however is less affected by Cd and Pb-Cd together than Pb alone. Erythrocyte acetylcholinesterase activity though decrease in all groups, is not significant.
Document emailed within 1 workday
Related Documents
Perí, S.I.; Arrieta, M.A.; Fink, N.E.; Salibián, A. 1998: Delta-aminolevulinic acid dehydratase (ALAD) activity in blood of Bufo arenarum (Anura) Biological Research 31(4): 339-342Firbas, W.; Seiller, W.; Welleschik, B.; Wicke, W. 1971: Acetylcholinesterase activity in the organ of Corti of albino rats following short-term exposure to sound Monatsschrift für Ohrenheilkunde und Laryngo-Rhinologie 105(6): 237-243
Pelissier, C.; Tack, D.L.; Gras, G. 1982: Effect of temephos on the acetylcholinesterase activity of the brain of Tilapia guineensis. 2: Experimental study of 24-hour exposure to the toxic compound Toxicological European Research. Recherche Europeenne en Toxicologie 4(6): 309-314
Morozova, I.I.; Morozov, A.V.; Dushkin, M.I.; Dolgov, A.V.; Medvedeva, I.N. 1985: Effect of changes in the oxygen level on cholesterol esterase activity of the liver of intact rats and rats subjected to chronic hypoxia Voprosy Meditsinskoi Khimii 31(6): 60-62
Pillai, A.; Laxmipriya; Rawal, A.; Gupta, S. 2002: Effect of low level exposure of lead and cadmium on hepatic estradiol metabolism in female rats Indian Journal of Experimental Biology 40(7): 807-811
Grabecki, J.; Jarkowski, M.; Michalewicz, L. 1981: Lead exposure of selected population groups. II. the lead level of the blood and delta-aminolevulinic acid level of the urine in the workers in a modern lead and zinc plant Roczniki Panstwowego Zakladu Higieny 32(5-6): 439-447
Bondarenko, T.I.; Miliutina, N.P.; Shustanova, T.A.; Mikhaleva, I.I. 1999: Regulatory effect of delta sleep-inducing peptide on the activity of antioxidant enzymes in erythrocytes and tissues of rats during cold stress Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 85(5): 671-679
Hayashi, M. 1983: Lead toxicity in the pregnant rat. I. the effect of high-level lead on delta-aminolevulinic acid dehydratase activity in maternal and fetal blood or tissues Environmental Research 30(1): 152-160
Matin, M.A.; Masih, A.H.; Kar, P.P. 1982: Paraoxon-induced changes in the level of cerebral acetylcholinesterase activity in diabetic mice Journal of Pharmacy and Pharmacology 34(7): 457-458
Dudka, J.; Szczepaniak, S. 1995: Evaluation of the combined effect of copper chloride and sodium nitrate on blood methemoglobin and tryptophan level in rats (subchronic exposure) Roczniki Panstwowego Zakladu Higieny 46(2): 169-174
Skopec, F.; Bajgar, J.; Vondrácek, V.; Jep, V. 1982: Changes in acetylcholinesterase and butyrylcholinesterase activity after whole-body irradiation in rats Sbornik Vedeckych Praci Lekarske Fakulty Karlovy Univerzity V Hradci Kralove. Supplementum 25(3-4): 327-334
Nazarov, I.B.; Baboshina, O.V.; Rogozkin, V.A.; Tsyplenkov, P.V. 1990: The effect of physical exertion on the activity of calpains and myeloperoxidase level in skeletal muscles of rats Ukrainskii Biokhimicheskii Zhurnal 62(3): 101-105
Slavíková, J.; Vlk, J.; Hlavicková, V. 1982: Acetylcholinesterase and butyrylcholinesterase activity in the atria of the heart of adult albino rats Physiologia Bohemoslovaca 31(5): 407-414
Morgan, J.M.; Burch, H.B. 1975: Erythrocyte delta-aminolevulinic acid dehydratase activity as a measure of lead exposure Journal of Laboratory and Clinical Medicine 85(5): 746-755
Zabludovskiĭ, A.L.; Zhulin, V.V. 1985: Effect of intrauterine ethanol exposure on higher nervous activity and on protein and lipid metabolic indices of the brain in rats Biulleten' Eksperimental'noi Biologii i Meditsiny 99(5): 545-548
Narce, M.; Poisson, J.P. 1984: In vitro study of delta 6- and delta 5-desaturations of linoleic and dihomo-gamma-linolenic acids during the development of arterial hypertension as a function of age in spontaneously hypertensive rats (SHR) as compared to normotensive rats (WKY) Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 178(4): 458-466
Moshkov, K.A.; Nikolaev, I.V.; Zaĭtsev, I.V.; Bul'on, V.V.; Burmistrov, S.O. 1986: Effect of ethanol on the level of biogenic amines and activity of energy metabolism enzymes in rats subjected to extreme conditions Molekuliarnaia Genetika Mikrobiologiia i Virusologiia 11: 30-36
Chakrabarti, S.K.; Brodeur, J.; Tardif, R. 1975: Fluorometric determination of delta-aminolaevulinate dehydratase activity in human erythrocytes as an index to lead exposure Clinical Chemistry 21(12): 1783-1787
Sazanov, A.V.; Tsirkin, V.I.; Dvorianskiĭ, S.A. 2000: Effect of the long-term exposure of the isolated myometrium from nonpregnant rats to serum from pregnant women on its contractile activity and the beta-adrenergic reactivity Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 86(1): 103-112
Németh, S. 1978: Effect of hormonal responses during stress on the level of metabolism with particular respect to glycogen content and phosphorylase activity in the liver of repeatedly injured rats Bratislavske Lekarske Listy 70(4): 449-458