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Advances in experimental paracoccidioidomycosis using an isogenic murine model

Singer-Vermes, L.M.; Burger, E.; Russo, M.; Vaz, C.A.; Calich, V.L.

Archives of Medical Research 24(3): 239-245

1993

ISSN/ISBN: 0188-4409
PMID: 8298272
Document Number: 421026
An experimental murine model of Paracoccidioides brasiliensis infection which allowed several parameters of host-parasite interactions to be investigated is described. Cellular immune responses, macrophages, delayed-type hypersensitivity reactions, humoral immune responses, specific recognition patterns, polyclonal activation of B cells and responses to heterologous antigens are discussed.

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