Neurosyphilis presenting with optic neuropathy. Report of a case and review
Pelfrene, E.; Michielsen, W.; Voet, D.; Hanssens, M.; Afschrift, M.; De Laey, J.J.
Acta Clinica Belgica 48(5): 324-330
1993
ISSN/ISBN: 1784-3286 PMID: 8291341 Document Number: 417184
A patient with neurosyphilis, presenting with severe ocular impairment due to optic neuropathy, is described. In such a case, a low index of clinical suspicion and improper use of syphilitic serologic tests may delay diagnosis. However, specific tests of serum and cerebrospinal fluid are mandatory for the diagnosis. Treatment evaluation necessitates the follow-up of serology and cerebrospinal fluid cell count. Recent changes of therapy recommendations in subjects with neurosyphilis and in those syphilitic patients co-infected with HIV are mentioned.