Bilateral optic neuropathy, acral gangrene and visceral ischaemia as a rare presentation of calciphylaxis: A case report
Komurcu, H.Ferhan.; Basar, E.; Kucuksahin, O.; Uz, E.; Orhun Yavuz, H.Sibel.; Anlar, O.
Jpma. Journal of the Pakistan Medical Association 66(10): 1324-1326
2016
ISSN/ISBN: 0030-9982 PMID: 27686313 Document Number: 687997
We report a case with calciphylaxis very rarely presenting with bilateral optic neuropathy, acral gangrene and visceral ischaemia. Bilateral papilloedaema was found in a 43 year-old female with chronic renal failure. Acral dry gangrene was observed. Pathological examination of her amputated thumb revealed calcification, thrombi, obstructive endovascular fibrotic areas in the walls of arteries. She was diagnosed with calciphylaxis. Bilateral optic neuropathy was defined secondary to calciphylaxis. Abdominal computerized tomography revealed prominent calcifications in mesenteric, spleen and renal arteries. She died eight months after the diagnosis. Calciphylaxis should be considered in the differential diagnosis of the optic neuropathy.