Use of arylsulfenylchlorides for cleaving fibrinogen at methionine residues
Iakunitskaia, L.M.; Ermolaeva, O.M.; Samartsev, M.A.; Kulikov, S.V.
Bioorganicheskaia Khimiia 19(3): 373-375
1993
ISSN/ISBN: 0132-3423 PMID: 8489535 Document Number: 416032
Conditions for the fibrinogen fragmentation with 2-pyridyl-or o-nitrophenylsulfenylchloride were proposed. Resulting mixture of fragments is identical to the mixture prepared by the cyanogen bromide treatment and is suitable as supplementary analytical reagent in the determination of the tissue plasminogen activator (TPA) activity with a chromogenic substrate.
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