Febantel, a new broad-spectrum anthelminthic

Wollweber, H.; Kölling, H.; Widdig, A.; Thomas, H.; Schulz, H.P.; Mürmann, P.

Arzneimittel-Forschung 28(12): 2193-2195

1978


ISSN/ISBN: 0004-4172
PMID: 582930
Document Number: 4145
N-(2-[2,3-Bis-(methoxycarbonyl)-guanidino]-5-(phenylthio)-phenyl)-2-methoxyacetamide (febantel, Rintal) is a new compound which is highly active against various species of nematodes and cestodes in mice, rats, dogs, sheep and cattle. In sheep and cattle a single oral dose of 5 mg/kg resulted in an almost complete elimination of larval and adult intestinal nematodes as well as Dictyocaulus. The compound was well tolerated by all animals tested.

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Febantel, a new broad-spectrum anthelminthic