The current aspects of seroepidemiological research in combined foci of leishmaniasis
Goncharov, D.B.; Saf'ianova, V.M.; Gracheva, L.I.
Meditsinskaia Parazitologiia i Parazitarnye Bolezni 1: 39-42
1993
ISSN/ISBN: 0025-8326 PMID: 8336651 Document Number: 414422
The authors analyze the results of C-ELISA, used in screening of the population in combined foci of zoonotic cutaneous leishmaniasis and visceral leishmaniasis in two types of landscapes in Turkmenistan. In the deltas, on the plains at the Kopet-Dag hills, the highest share (4%) of the population with such antibodies lived in the sandy deserts in the interfluvial areas of southern-eastern Turkmenistan. The authors have validated the criteria for the assessment of the endemicity level of leishmaniasis foci with due consideration for various incidence rates of visceral and zoonotic cutaneous leishmaniases and the specific features of the immune response in these nosologic forms. They suggest that a positive serologic response be considered as the basic criterion of a visceral leishmaniasis focus, and the disease incidence and the number of subjects who had had this disease in the focus--the basic criterion for the assessment of a zoonotic cutaneous leishmaniasis focus endemicity.