Evolution of the hemagglutinin gene of human influenza a virus H3 subtype
Petrov, N.A.; Netesov, S.V.; Blinov, V.M.; Vasilenko, S.K.
Molekuliarnaia Genetika Mikrobiologiia i Virusologiia 11: 7-14
1986
ISSN/ISBN: 0208-0613 PMID: 3821759 Document Number: 4118
An evolutional tree of human influenza viruses of the H3N2-subtype is suggested on the basis of combined published primary structures of the hemagglutinin HA1-subunit. Possible differences between natural and sequenced structures are discussed. A tendency to reversions in the course of antigenic draft within the subtype has been revealed to support the hypothesis of limited antigenic evolution within a single subtype.
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