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Secondary immunodeficiencies in the pathogenesis of protracted forms of intestinal infections and the prospects for their immunocorrection

Iushchuk, N.D.; Frolov, V.M.; Peresadin, N.A.

Terapevticheskii Arkhiv 65(11): 12-15

1993

ISSN/ISBN: 0040-3660
PMID: 8108788
Document Number: 409137
Acute intestinal infections (AII) are characterized by marked defects of immune homeostasis. These were not related to the disease etiology though depended on the infection severity and manifested with T-lymphopenia, reduced count of circulating T-helper cells in normal amount of T-suppressor cells. This resulted in low immunoregulatory index (CD-4/CD-8). Immunological criteria have been determined indicative of the tendency to formation of a protracted AII course and long-term persistence of the agent in the host.

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