Physical separation of three soluble malarial antigens from the serum of chickens infected with Plasmodium gallinaceum

Lykins, J.D.; Smith, A.R.; Voss, E.W.; Ristic, M.

American Journal of Tropical Medicine and Hygiene 20(3): 394-401

1971


ISSN/ISBN: 0002-9637
PMID: 4996704
Document Number: 40757
Three precipitating serum soluble antigens (SAg 1, SAg 2, SAg 3) were demonstrated in the serum of fowls that had been injected with Plasmodium gallinaceum 12 to 80 hours previously. These antigens were detected when the fowls were tested by double diffusion in gel against an antiserum obtained from fowls that survived the infection. The three antigens showed a molecular weight relationship of SAg 1 > SAg 2 > SAg 3 based on their diffusion in gel and elution from Sephadex G-200.

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