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A clinical and histological comparative study of the effect of nifedipine and phenytion on human gingiva

Shoieb, M.A.; Fathy, L.M.; Abu-el-Dahab, O.; el-Sherbiny, M.M.

Egyptian Dental Journal 39(4): 555-558

1993

ISSN/ISBN: 0070-9484
PMID: 9588123
Document Number: 406082
Ten patients manifesting gingival enlargement were chosen for this study. Five patients had been treated with 4 mg nifedipine per day as a treatment for angina pectoris, while the other five patients treated with phenytion as an anticonvulsant drug. Clinical and histological data showed that nefidipine induced gingival hyperplasia which is of close similarity to that induced by phenytion despite the differences in target tissue.

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