The use of glutathione as a protector agent in hypoxic exposure
Korneev, A.A.; Komissarova, I.A.; Nartsissov, I.R.
Biulleten' Eksperimental'noi Biologii i Meditsiny 116(9): 261-263
1993
ISSN/ISBN: 0365-9615 PMID: 8117995 Document Number: 405728
The antihypoxic effect of glutathione was studied in a pressure chamber of acute hypoxic hypoxia and in the perfused heart of non-inbred rats. The body's natural metabolite glutathione was found to show the properties of an active antihypoxant, a protector of energy action. The mechanism of this action of glutathione may be associated with decreased hyper-recovery of the mitochondrial respiratory chain and with its restored capacity to synthesize ATP at the first point of oxidative phosphorylation.
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