Growth and functional activiy of the adrenal cortex during fetal development during exposure to hypoxic and hyperoxic conditions
Nemets, M.G.; Tarasova, I.S.
Biulleten' Eksperimental'noi Biologii i Meditsiny 82(12): 1428-1429
1976
ISSN/ISBN: 0365-9615 PMID: 1035503 Document Number: 101720
A study was made of lipid, cholesterol, and ascorbic acid content in the adrenal cortex of rabbit fetuses developing under conditions of normal pregnancy and under the action of hypoxic and hyperoxic exposures during its third trimester. It appeared that in normal pregnancy the adrenal cortex was activated, this being associated with the adaptive motor reactions of the developing fetus. The action of moderate hypoxic exposures led to a greater activation of moderate hypoxic exposures led to a greater activation of the adrenal cortex, this being expressed in a marked fall of lipid, cholesterol and ascorbic acid content. The weight of the total muscle mass and of the fetuses increased as a whole. The adrenal cortex became disactivated under conditions of the hyperoxic exposures; this is expressed in a marked increase in the content of the mentioned formations. The weight of the total mass and of the fetuses decreases.